Improving Pharmaceutical Aerosol Delivery During Noninvasive Ventilation: Effects of Streamlined Components
نویسندگان
چکیده
منابع مشابه
Improving aerosol drug delivery during invasive mechanical ventilation with redesigned components.
INTRODUCTION Patients receiving invasive mechanical ventilation with an endotracheal tube (ETT) can often benefit from pharmaceutical aerosols; however, drug delivery through the ventilator circuit is known to be very inefficient. The objective of this study was to improve the delivery of aerosol through an invasive mechanical ventilation system by redesigning circuit components using a streaml...
متن کاملAlbuterol delivery during noninvasive ventilation.
HYPOTHESIS Albuterol delivered during noninvasive positive-pressure ventilation is affected by use of a nebulizer or metered-dose inhaler (MDI) and whether the leak port is in the hose or the mask. METHODS A lung model that simulated spontaneous breathing at 20 breaths/min was used. A bi-level positive-airway-pressure ventilator (Respironics S/T30) was set for an inspiratory positive airway p...
متن کاملBronchodilator delivery during simulated pediatric noninvasive ventilation.
BACKGROUND Noninvasive ventilation (NIV) is usually applied using bi-level positive airway pressure devices, and many of these devices use a single-limb patient circuit with an integrated leak port to purge the circuit of exhaled carbon dioxide. Sometimes bronchodilator therapy is indicated in pediatric patients, but there have been no studies of the optimal nebulizer position, with respect to ...
متن کاملAerosol Therapy During Noninvasive Ventilation or High-Flow Nasal Cannula.
Noninvasive ventilation (NIV) and high-flow nasal cannula (HFNC) are increasingly used for patients with acute respiratory failure. Some patients receiving these therapies might also benefit from inhaled drug delivery. Thus, it is attractive to combine aerosol therapy with NIV or HFNC. The purpose of this paper is to review the available evidence related to the use of inhaled aerosols with NIV ...
متن کاملAerosol delivery during invasive mechanical ventilation: a systematic review
BACKGROUND This systematic review aimed to assess inhaled drug delivery in mechanically ventilated patients or in animal models. Whole lung and regional deposition and the impact of the ventilator circuit, the artificial airways and the administration technique for aerosol delivery were analyzed. METHODS In vivo studies assessing lung deposition during invasive mechanical ventilation were sel...
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ژورنال
عنوان ژورنال: Annals of Biomedical Engineering
سال: 2013
ISSN: 0090-6964,1573-9686
DOI: 10.1007/s10439-013-0759-9